HOLLYWOOD'S most popular actors haven't held back in their opposition to US President Donald Trump and his newly imposed immigration ban at the Screen Actors Guild Awards.

Emma Stone, Bryan Cranston, Ashton Kutcher and Julia Louis-Dreyfus attacked President Donald Trump at the SAG Awards - but one speech stole the show.

The crowd erupted when Stranger Things' win for Best Ensemble in a Drama Series was perhaps the biggest surprise of the night, especially since it took out none of the individual prizes.

Actor David Harbour's acceptance speech was similarly unexpected, but equally well-received.

"This is unreal. I'd just like to say that with all that's going on tonight, it's hard to celebrate the already celebrated Stranger Things.

"We are united in that we are all human beings and we're all here together on this painful and mysterious ride that is being alive."

"We will repel bullies, we will shelter freaks and outcasts, we will hunt monsters, and when we are lost, we will punch some people in the face, and we will do it all with soul, with heart and with joy. We thank you for this responsibility."

Harbour's speech was stirring, but it was his Stranger Things co-star Winona Ryder, standing alongside him, who most were glued to: Ryder seemed to exhibit just about every human emotion during his speech, grimacing and gurning oddly. It was hard to look anywhere else:

Indeed, viewers were transfixed by the bizarre display, which seemed as though Ryder was competing in a one-woman contest to give the internet as many reaction gifs as possible:

Host Ashton Kutcher opened the ceremony by welcoming everyone watching at home and then saying angrily, "... and everyone in airports that belong in my America."

Kutcher's reference to immigration restrictions imposed by Trump that have excluded immigrants from seven nations and tied up others seeking entry into the country drew thunderous applause.

Loud cheers greeted statements denouncing the new immigration restrictions by Louis-Dreyfus, and a celebration of diversity by Taylor Schilling, who spoke after her series Orange is the New Black won best comedy series.

Scandal actress Kerry Washington addressed that criticism during the ceremony's introduction. She told the audience, "Actors are activists no matter what."

During the ceremony, the whole room erupted and yelled out "Power to the People".

The two biggest shock wins of the night were Hidden Figures, which got the Best Picture award, and Denzel Washington's gong for his role in Fences.

Full SAG Awards winners list:

Outstanding Performance by a Cast in a Motion Picture

Captain Fantastic
Fences
*** WINNER: Hidden Figures
Manchester by the Sea
Moonlight

Outstanding Performance by a Male Actor in a Leading Role

Casey Affleck, Manchester by the Sea
Andrew Garfield, Hacksaw Ridge
Ryan Gosling, La La Land
Viggo Mortensen, Captain Fantastic
*** WINNER: Denzel Washington, Fences

Outstanding Performance by a Female Actor in a Leading Role

Amy Adams, Arrival
Emily Blunt, The Girl on the Train
Natalie Portman, Jackie
*** WINNER: Emma Stone, La La Land
Meryl Streep, Florence Foster Jenkins

Outstanding Performance by a Male Actor in a Supporting Role

*** WINNER: Mahershala Ali, Moonlight
Jeff Bridges, Hell or High Water
Hugh Grant, Florence Foster Jenkins
Lucas Hedges, Manchester by the Sea
Dev Patel, Lion

Outstanding Performance by a Female Actor in a Supporting Role

*** WINNER: Viola Davis, Fences
Naomie Harris, Moonlight
Nicole Kidman, Lion
Octavia Spencer, Hidden Figures
Michelle Williams, Manchester by the Sea

Outstanding Performance by a Stunt Ensemble in a Motion Picture
Captain America: Civil War
Doctor Strange
*** WINNER: Hacksaw Ridge
Jason Bourne
Nocturnal Animals

Outstanding Performance by an Ensemble in a Drama Series

The Crown
Downton Abbey
Game of Thrones
*** WINNER: Stranger Things
Westworld

Outstanding Performance by an Ensemble in a Comedy Series

The Big Bang Theory
Black-ish
Modern Family
*** WINNER: Orange Is the New Black
Veep

Outstanding Performance by a Male Actor in a Drama Series

Sterling K. Brown, This Is Us
Peter Dinklage, Game of Thrones
*** WINNER: John Lithgow, The Crown
Rami Malek, Mr. Robot
Kevin Spacey, House of Cards

Outstanding Performance by a Female Actor in a Drama Series

Millie Bobby Brown, Stranger Things
*** WINNER: Claire Foy, The Crown
Thandie Newton, Westworld
Winona Ryder, Stranger Things
Robin Wright, House of Cards

Outstanding Performance by a Male Actor in a Comedy Series

Anthony Anderson, Black-ish
Tituss Burgess, Unbreakable Kimmy Schmidt
Ty Burrell, Modern Family
*** WINNER: William H. Macy, Shameless
Jeffrey Tambor, Transparent

Outstanding Performance by a Female Actor in a Comedy Series

Uzo Aduba, Orange Is the New Black
Jane Fonda, Grace and Frankie
Ellie Kemper, Unbreakable Kimmy Schmidt
***WINNER: Julia Louis-Dreyfus, Veep
Lily Tomlin, Grace and Frankie

Outstanding Performance by a Male Actor in a Miniseries or Television Movie

Riz Ahmed, The Night Of
Sterling K. Brown, The People v. O.J. Simpson: American Crime Story
*** WINNER: Bryan Cranston, All the Way
John Turturro, The Night Of
Courtney B. Vance, The People v. O.J. Simpson: American Crime Story

Outstanding Performance by a Female Actor in a Miniseries or Television Movie

Bryce Dallas Howard, Black Mirror
Felicity Huffman, American Crime
Audra McDonald, Lady Day at Emerson's Bar & Grill
*** WINNER: Sarah Paulson, The People v. O.J. Simpson: American Crime Story
Kerry Washington, Confirmation

Outstanding Performance by a Stunt Ensemble in a Television Series
*** WINNER: Game of Thrones
Marvel's Daredevil
Marvel's Luke Cage
The Walking Dead
Westworld

53rd Annual SAG Life Achievement Award

Lily Tomlin